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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c2de346f621d7db0ab3d4e941f1c8f66baec142f8d57501a744c57a20543b3' 
  AND token = 'YgZePa+sxF9C0xcMkfop02T6DE2WWcEr/EXrsD+4rN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}