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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41514706502484622eba9716cfeca8da294f8b2dbeca3820480c77b253c458b' 
  AND token = 'FALE88aR3AOxxNK16bXWzM5DS8k8NKst/CDEoa8ZgAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}