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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e95b0f4219fe6de71f8b22828f5a5de4cafc58d123c70900ca0b41beeb68f6d' 
  AND token = 'VRmwRy6pprS8mlwkBKTXS9tmwzE26F1TzBHuXp50xxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}