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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c20e7a2f014bc40a5c735745e09f270cd2c5bec0a0eb57c16d4c5dfc4718d587' 
  AND token = 'zkJsGVTYieDpWKdqzbIQzL5V1hLuNyjHliDssVbOttc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}