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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '281735d54a3814bc5cbed48d0331e3f3ed21c09e4ee0b6c12997f16638efcb0b' 
  AND token = '+WPx+5KHVNj8pHw6QWFWQvM47/er0RAazpgW2PWbZ28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}