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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f765263b84ec27d678cb8917bb024128ed91014d987ad75ad1a0bafba4a2676e' 
  AND token = '46ZDQ4EcwjbLAFj3tPxIJdBVF2qKgqW59iHIUF93Ue4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}