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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b886f9d78dabe44999aed7d711b2a36eb32d07c2481ea83a7c1b24ba50c06ba' 
  AND token = 'HtkFTtskjX3sUHTsBZprJl45hE8UKMyCIz1ttStTl1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}