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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b44ed4c1a959c7e21a7cd78557da517ccad34bd1826a39762ff93819047cd547' 
  AND token = 'Lq7vdBRSpIsOXPUwbck1Odc2hP8e5/poOyuilFEiJdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}