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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '706b54118af87a0ebd36290d586360218c3da73fb926ab7dcbdd9ac7986c14d4' 
  AND token = '/DfPcG74DB+AYdU0zmvaObtPQq8GY2yp8s2spX37YKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}