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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d43e0a2db726d2f394361ee744dafeba9520515638bc02f7b35a6214edcf69b' 
  AND token = 'jRCF5KgmQ4NRJyIvSaJ3/jZMja8bp7bYoN0CVgn3Y/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}