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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8743779c6fee42af88c70f22861c65a4debd15a7364cbf3529367781d36627b4' 
  AND token = 'F3nu8J3gz4aJ37AG53blW3aPTXDDZkuPId5i078dRlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}