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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd4da4b71f62a1cc637693b11d97f158d95caa4e4b8a19a2f4461a299191d4c' 
  AND token = '+OjuO9C5cDT5e/YT4gBMuZQFbatj02xZCmG3NnLyFjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}