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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a610ae199eaccf788785dd914ef668bb8e2bdcf175ef0a1d2cbf85b55b1f32d6' 
  AND token = '4Z5CSnWsfuSVaDqmvuM7BUIBtOLq4NFTXIG51d2gDoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}