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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6105fe724fa7fff2d5b1853712d18604cf1f192b9422ea461d323bbe4fd17de8' 
  AND token = 'b0icaLCJ6nkTO8mM6jY3tEo155aZdDlNb6eDxx5PqqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}