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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c95d90975814386d65bb5032025cfb85b52c906687a387de6a63eb655c4998c' 
  AND token = 'YMNm2IIp6GaI8F23JL+ykWVcGf3kk9wiDiiTsMF1Zsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}