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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d635d929df395950194671f1292ae0f9ca5579809cfe7a68f72ec9ece0765a3' 
  AND token = '6YorSJ62iJrXjsbRuUuAvB3C9iPR4A/ufdpmiMhPv54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}