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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c73ed13e2b06f809b40f0ae76d8101995a393d25704d5f8e59b938dc19ae564d' 
  AND token = '7uMWNBX1+hJoOWNgr5NTKUtf33IbDurEBgNj80SksLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}