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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62f66782806b8bf45081ff0f82e6b0cabed31280eae2a5e5b74b756dbe0207dd' 
  AND token = 'u+C2LbhrTKAJZYiinDXG7XdJxaJDvVCihT3mNVFYOAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}