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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63a7428813c7b21d8fd723bf2c61ad46c86aa771143be82385ab9a0dd1f1a8b5' 
  AND token = 'XMDMZ/V904SaYBb+AIHfjKUevzSaLcws9ZZEibXj+58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}