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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3395ee493349549fd377c496a81392aec9a1277354c2020ff90e10dd7396b14' 
  AND token = '21NVid14w7Ylx4VsylY/CCFcCN+T+Qht7mHWGG5e+PU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}