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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66254290927ef1d8eee0f1b991a208fc5c8f05270d803177aaeaf2f09248bdc8' 
  AND token = 'qUh7n1yJlaqUd2ZvJpf4hpU2KryMhsnO4raalumhuQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}