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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7b09f25790e4b9179cb8ab639dfb286e33ef049c892b832025ea3c010e752f3' 
  AND token = 'MSjniq/V9cPrqxjggPhoI3u/uxpGZCcsqc1AkkoLSjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}