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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7fa0a7dbf2caf189770f83add786d2faf6ec8b4a863ed1da2282fd2b0c115ab' 
  AND token = 'wUqFykrbt1UGzP3/877Jx/N9SKSXIAGYxmkyrCbCcVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}