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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61ac1642dbed13567cc2140cc1e7b4f5ec00559cb8e5811f6127272f2b6c4c4b' 
  AND token = '/MfK21nszmjrvRxdjESVV9NGcDS2I1vSdSZ01yE9FtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}