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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '747767c131f3834f869fd54adbc7535f49f1dc72d09f526451d5aee9665e8917' 
  AND token = 'tRFDxloKBP1wPVSe4IvDR/Mg5pB4DekMbZFMC20dDEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}