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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '018a55b6527fb5191853e4506185fa3c2977e740776d1b71a77f20689749f7c6' 
  AND token = 'dAsLEAfI4/wkIyqUw1huixOeCSXGlRbv8kcfJFyHHAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}