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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b893f9aadb31d54125a06436ba1ea948b7d635201e3985be57cd9556f60367' 
  AND token = 'SNQYs6GrSLQ0gJBDCd9pGzJDnXiF+0P632NQLbmyTRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}