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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ab84ab68d0795cdfed0feb0e8b40cdcd972b99fc713ce9b930b0df06a9ed7d' 
  AND token = 'fiMLeViu3xGt9f7qrEuKcLGbIVF0OIPV8+YzbSl1JZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}