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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd34a4c6374d8049297a3c7ef49e9ecc130ee8a86dc6e51b802b798057409b04' 
  AND token = 'VM+NgWQqMpmN/4xTMbbbPASYhPfglS6hI8ESPKs0BQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}