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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44288d7ed6c8f5f83319bfae9c8787867aae9020cdc328f6e3dcb36d905ec88c' 
  AND token = 'BgugVhVMrHZT/7yrpA9WJYVttiXnYac+QHnSeyKcj0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}