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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd30e0fa23c8876466fd7eec260ccdd749c2a2629547593aaee4615f018f85983' 
  AND token = 'F2/guOpA97oXk0tCGg7NR9bWV7EQfXF4LW0Wr3PKzc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}