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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbf4c61dfd4222fd60df0c2db5a9cef880e34055f7a1b82eb43bdd1d96cc86f6' 
  AND token = 'W9+egQmcy/ag0zGDlHWQ2iTEujcgAPQXT3rh2bzerXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}