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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f052eabff00f4d44fcae29e11cef7697bac00b6ccbbe826e543b6c50870c4e02' 
  AND token = 'gc2uB7rFYSqilulXUbK3PWpdfLh2MkbyhYgLMWwx+4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}