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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fe648c0484b5f3cce39776082205221d283888e148ae122dd8a0f818481c592' 
  AND token = '9IF4NryjB4Du99S1Us+bERXlOaFX6s8zemEOo02ZglM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}