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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede8b92e405c5419eead34b927ae1b7dbdb6aa5a003fe99fe6178d05c4072a65' 
  AND token = 'aKjDEPSLJC1fuk+c/tQCBEj5D/l9WFTWtb160ZgT2fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}