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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69aa4d363a206bb1b3c0158b8d830c7b3bad00720aa14bbc4ab4e60eb9d21d99' 
  AND token = 'ShIqWkdfcrPhH+ILjp0VyOhS0mmVAulDUH0uE+BaQQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}