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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8eef33c225e4ad89ca87c37df8f5188b2d3af402b91a923b057c412a2a85049' 
  AND token = 'yQUIxGk+tExUlkl+3Y1bfRJvHlXgELe6Gc06FJo9Q14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}