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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b66f2e328efbaa85fbff15da6ecb0c32924f2d4077a6d55eaf7ec50984cdf2' 
  AND token = 'NzsFXrKB3DAbHoNy70HABHBRPt1+9DMU5FQKCThYhHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}