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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10ca7f06fb007a9173bf372e1c165f6898bbf2e7b5cba73d55934d7be356b713' 
  AND token = '6TTeSKikcsDN/oqyTi9CcEAPf71Pii9YHtDtBTGOGiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}