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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f4c83befc5bcfadd5df55e3c9cb0e098b0869ccb1d7462d99fd99484a51c0c' 
  AND token = '6VOpvI/bG6tSVFCyVOvOB0zpeNCQgAJKC0LnPyUFLt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}