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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f5740e3072f49e37295fc9859d6a6c679954217aa05133e02c509be51e6af8c' 
  AND token = 'PsoxjP59AAIwUcuxf42OlRHcCBBCFhkskLVFKFzNA40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}