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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc615c85d8c78aa01ed3c7e0e898c38e37920e31d04cb078da749247050482a1' 
  AND token = 'f4m0dp1lHyxCedzpdWTIGoQWzBSluaGEzUbCDiaV+TY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}