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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8bb91e45e0ea2b7a73e4b0bd18a8e29e6054c4bc996aa00242704635c1aa5b' 
  AND token = 'xoyxV3j6DPgWIHLLXPMGBhU6+7p9SRLOaA+uqD2vhRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}