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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fe06233d027d426683375f27b7edcd425f9509f835917c7496ed6487e75e652' 
  AND token = 'RyuQnTwKT+pve6EoTB88y6Vzc+wq2jK+rAFUFn0HnSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}