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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e0505ffa7a83a80d47a61ae3e9465837bade69fd6c132f365ead613d1f7c531' 
  AND token = '/8D5StIYrGU43DpWJYX7RCIrz3OiK1hyCS1AHQ36G+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}