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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f365ce7d3c845b9cf537db756b0087b0b77895743441bbea930c07dd6ed421' 
  AND token = 'C5reyt33TF8cJgAC/yM2pUEVX1JIIS9cVITFjO7VYvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}