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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c9581bbad0d4d8e63518f4085d84ab32800e00005ada4208fbe1e7264b1e3c' 
  AND token = 'el1ZKO6y/IQY7Jq3Y4mgslB7CcKatTYU2pfi7OarpTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}