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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04189d39355b991eb45a9e952e3d316a1ae7a0ab7f03f7713f3e2d953625857c' 
  AND token = '54k6GC0JtT0GoTnyZux57IWf/Gkn6c8H660XM9TatkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}