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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd53cca0fdd5b7d46528ae6b637de201dcbb435a8f092e4b88f39413c42eac3' 
  AND token = 'OAtD6fkT0q/WFp6Ca8K+24Vd7kFQ2EZEir65ZEMCzIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}