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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80fc8a18aab30d74ab38b9d7a579abda6b7ac8425000d069c31dc7bba5ccb1ed' 
  AND token = 'UEbeVu+gUFzKTLBrzovCoZcY6T8bhWfyWZru47DtqVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}